Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection.

Joseph Bertin Kadji FassiHermine Boukeng JatsaUlrich Membe FemoeValentin GreigertJulie BrunetCatherine CannetChristian Mérimé KenfackNestor Gipwe FeussomEmilienne Tienga NkondoAhmed Abou-BacarAlexander Wilhelm PfaffRené KamgangPierre KamtchouingLouis-Albert Tchuem Tchuenté

Published in: PLoS neglected tropical diseases (2022)

These results demonstrated that a low-protein diet reduced the schistosomicidal, antioxidant, anti-inflammatory, and immunomodulatory activities of praziquantel.

Keyphrases

anti inflammatory
protein protein
physical activity
amino acid
oxidative stress
binding protein