A mitochondrial regulator protein, MNRR1, is elevated in the maternal blood of women with preeclampsia.

Manaphat SuksaiRoberto RomeroMariachiara BoscoFrancesca GotschEunjung JungPiya ChaemsaithongAdi L TarcaDereje W GudichaNardhy Gomez-LopezMarcia Arenas-HernandezArun MeyyazhaganLawrence I GrossmanSiddhesh ArasTinnakorn Chaiworapongsa

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2024)

MNRR1, a mitochondrial regulator protein, is elevated in the maternal plasma of women with preeclampsia (both early and late) at the time of diagnosis. These findings may reflect some degree of mitochondrial dysfunction, intravascular inflammation, or other unknown pathologic processes that characterize this obstetrical syndrome.

Keyphrases

oxidative stress
pregnancy outcomes
early onset
birth weight
protein protein
transcription factor
coronary artery
pregnant women
neoadjuvant chemotherapy
binding protein
case report
small molecule
gestational age