ERK mediates interferon gamma-induced melanoma cell death.

Ameya ChamphekarRachel HeymansJustin SacoGuillem Turon FontCynthia GonzalezAnne GaoJohn PhamJune LeeRyan MaryoungEgmidio MedinaKatie M CampbellDaniel KarinDavid AustinRobert DamioseauxAntoni Ribas

Published in: Molecular cancer (2023)

Our results provide a new understanding of the IFNγ growth inhibition pathway, which will be crucial in defining mechanisms of immunotherapy response and resistance.

Keyphrases

cell death
dendritic cells
high glucose
signaling pathway
diabetic rats
cell proliferation
immune response
pi k akt
drug induced
cell cycle arrest
oxidative stress
skin cancer