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Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable.

Hirdesh KumarJessica KehrerMirko SingerMiriam ReinigJorge M SantosGunnar R MairFriedrich Frischknecht
Published in: Expert opinion on therapeutic targets (2019)
Plasmodium dUTPase and Ap4A could be drug targets in the malaria parasite.
Keyphrases
  • plasmodium falciparum
  • transcription factor
  • circulating tumor
  • genome wide
  • single molecule
  • cell free
  • copy number
  • emergency department
  • dna methylation
  • drug induced