Raphe Nuclei Echogenicity and Diameter of Third Ventricle in Schizophrenia Measured by Transcranial Sonography.
Mahnoush MahdiarNahid MohammadzadeAmirsina HomayooniFahimeh Haji AkhoundiFatemeh KashaninasabBabak ZamaniSeyed Vahid ShariatMohammadreza ShalbafanMohammad RohaniPublished in: Basic and clinical neuroscience (2023)
Schizophrenia is a disabling psychiatric disorder. Various neurotransmitters have a role in the pathophysiology of schizophrenia including Serotonin and dopamine. This study assessed the echogenicity of raphe nuclei (RN), as the main source of brain serotonin, and the diameter of the third ventricle (DTV), as an index of atrophy, by transcranial sonography (TCS) method in 30 patients with schizophrenia and 30 healthy controls. Based on the results, 23 patients (76.5%) and 15 controls (50%) showed decreased echogenicity of RN. There was a significant difference between the two groups in terms of the echogenicity of RN. Moreover, the DTV diameter was significantly larger in patients compared to controls.
Keyphrases
- end stage renal disease
- bipolar disorder
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- pulmonary hypertension
- magnetic resonance imaging
- mitral valve
- magnetic resonance
- patient reported outcomes
- coronary artery
- pulmonary arterial hypertension
- blood brain barrier
- subarachnoid hemorrhage
- cerebral blood flow