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Tirzepatide for the treatment of obesity: Rationale and design of the SURMOUNT clinical development program.

Carel W le RouxShuyu ZhangLouis J AronneRobert F KushnerAriana M ChaoSriram MachineniJulia DunnFarai B ChigutsaNadia N AhmadMathijs C Bunck
Published in: Obesity (Silver Spring, Md.) (2022)
The extensive assessment of once-weekly tirzepatide in the global SURMOUNT program will detail the clinical effects of this first-in-class glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist in chronic weight management.
Keyphrases
  • weight loss
  • quality improvement
  • metabolic syndrome
  • type diabetes
  • insulin resistance
  • body mass index
  • blood pressure
  • skeletal muscle
  • adipose tissue