Coordinated IgG2 and IgE responses as a marker of allergen immunotherapy efficacy.
Véronique Bordas-Le FlochNathalie BerjontThierry BatardNirupama VareseRobyn Elizabeth O'HehirWalter G CanonicaMenno C van ZelmLaurent MascarellPublished in: Allergy (2021)
We provide evidence for coordinated serum immune responses upon AIT in HDM-allergic subjects exhibiting high clinical benefit when compared with low responders. Assessing HDM-specific IgE, IgG2, and IgG4 in serum could be used as follow-up combined markers to support decision as to AIT continuation and/or adaptation.