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Cardiotoxicity and pharmacogenetics of doxorubicin in black Zimbabwean breast cancer patients.

Vincent Aketch NyangwaraTinashe MazhinduZedias ChikwambiCollen MasimirembwaThomas B CampbellMargaret BorokNtokozo Ndlovu
Published in: British journal of clinical pharmacology (2023)
This is the first study on the prevalence of DIC and associated genetic biomarker predictive evaluation in Zimbabwean breast cancer patients. The genetic frequencies observed in our study were different to those reported in other populations. A larger sample size with a longer follow-up time will be necessary in future studies.
Keyphrases
  • genome wide
  • risk factors
  • drug delivery
  • gene expression
  • copy number
  • genetic diversity