Green Synthesis of Antibacterial Nanocomposite of Silver Nanoparticle-Doped Hydroxyapatite Utilizing Curcuma longa Leaf Extract and Land Snail ( Achatina fulica ) Shell Waste.
Is FatimahHabibi HidayatGani PurwiandonoKhoirunisa KhoirunisaHasna Azizah ZahraRahmania AuditaSuresh SagadevanPublished in: Journal of functional biomaterials (2022)
Preparation of green synthesized silver nanoparticle (AgNPs)-doped hydroxyapatite (Ag/HA) utilizing Curcuma longa leaf extract and land snail ( Achatina fulica ) shell waste was performed. Physicochemical characteristics and antibacterial activity of Ag/HA composite as a function of Ag content was studied. Instrumental analysis such as XRD, SEM-EDX, TEM, and XPS were employed to characterize the nanocomposites. The physicochemical study revealed the maintained porous structure of HA after Ag immobilization, and from TEM analyses, it was found that the distributed spherical particles are associated with the dispersed Ag and have a particle diameter of around 5-25 nm. Antibacterial activity of the nanocomposite was evaluated against Escherichia coli , Staphylococcus aureus , Kliebsiella   pneumonia , and Streptococcus pyogenes . The results showed that the varied Ag content (1.0; 1.6; and 2.4% wt) influenced the nanoparticle distribution in the nanocomposite and enhanced the antibacterial feature.
Keyphrases
- quantum dots
- visible light
- silver nanoparticles
- highly efficient
- escherichia coli
- staphylococcus aureus
- epithelial mesenchymal transition
- climate change
- reduced graphene oxide
- biofilm formation
- heavy metals
- deep learning
- candida albicans
- anti inflammatory
- photodynamic therapy
- pseudomonas aeruginosa
- iron oxide
- bone regeneration
- optical coherence tomography
- solid phase extraction
- klebsiella pneumoniae
- methicillin resistant staphylococcus aureus
- mechanical ventilation