FGF19 promotes cell autophagy and cisplatin chemoresistance by activating MAPK signaling in ovarian cancer.

Wei ZhuMeiyuan HuangAbhimanyu ThakurYuanliang YanXiaoying Wu

Published in: PeerJ (2023)

FGF19 increases autophagy and chemoresistance in ovarian cancer by activating the p38 MAPK pathway. These results could point to FGF19 being a potential therapeutic target for ovarian cancer.

Keyphrases

signaling pathway
oxidative stress
cell death
pi k akt
endoplasmic reticulum stress
cell therapy
cancer stem cells
mesenchymal stem cells
climate change