Effects of endogenous GIP in patients with type 2 diabetes.

Signe Stensen Laerke Smidt Gasbjerg Liva S L Krogh Kirsa Skov-JeppesenAlexander H Sparre-UlrichMette H JensenFlemming Dela Bolette Hartmann Tina Vilsbøll Jens Juul Holst Mette Marie Rosenkilde Mikkel Bring Christensen Filip K Krag Knop

Published in: European journal of endocrinology (2021)

Using a selective GIP receptor antagonist during a meal, we show that endogenous GIP increases postprandial insulin secretion with little effect on postprandial glycaemia but is important for postprandial bone homeostasis in patients with type 2 diabetes.

Keyphrases

blood glucose
bone mineral density
type diabetes
blood pressure
soft tissue
metabolic syndrome
adipose tissue