Blood purification therapy in patients with severe COVID-19 requiring veno-venous ECMO therapy: A retrospective study.
Ali AkilStephan ZiegelerStephanie RehersErik Christian ErnstStefan FischerPublished in: The International journal of artificial organs (2022)
Treatment of a critically ill COVID-19 ARDS patients with combined VV ECMO support and hemoadsorption therapy led to a rapid and sustained hemodynamic stabilization, a control of the uncontrolled inflammatory response and an improvement in oxygenation. Given these signals pointing toward a patient-oriented benefit of extracorporeal hemoadsorption therapy in those patients, future controlled, randomized studies should focus on the investigation of the appropriate timing and dosing of this promising treatment modality.
Keyphrases
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- coronavirus disease
- inflammatory response
- sars cov
- end stage renal disease
- open label
- mechanical ventilation
- prognostic factors
- respiratory failure
- peritoneal dialysis
- clinical trial
- phase iii
- lipopolysaccharide induced
- lps induced
- cell therapy
- respiratory syndrome coronavirus
- quantum dots
- drug induced
- blood flow
- patient reported