Intracerebroventricular PROK2 infusion could increase the secretion of male reproductive hormones by stimulating the HPG axis.

Published in: Molecular biology reports (2024)

The present study findings demonstrated that icv PROK2 infusion induced the HPG axis. It could be suggested that PROK2 could be a potential agent in the treatment of male infertility induced by endocrinological defects.

Keyphrases

low dose
high glucose
drug induced
type diabetes
risk assessment
skeletal muscle
combination therapy
metabolic syndrome
replacement therapy