A non-genetic engineering platform for rapidly generating and expanding cancer-specific armed T cells.
Yi-Jou ChenMichael ChenTian-Lu ChengYi-Shan TsaiChang-Hung WangChe-Yi ChenTung-Yun WuShey-Cherng TzouKai-Hung WangJing-Jy ChengAn-Pei KaoShyr-Yi LinKuo-Hsiang ChuangPublished in: Journal of biomedical science (2023)
Collectively, the BsAb-armed T cell technology represents a simple, time-saving, and highly safe method to generate highly pure cancer-specific effector T cells, thereby providing an affordable T cell immunotherapy to patients.