Multistability in the epithelial-mesenchymal transition network.

Published in: BMC bioinformatics (2020)

Our results suggest that the multistability is broadly present in the EMT network across parameters and thus response of cells to signals may strongly depend on the particular cell line and genetic background.

Keyphrases

epithelial mesenchymal transition
induced apoptosis
signaling pathway
transforming growth factor
cell cycle arrest
endoplasmic reticulum stress
genome wide
cell death
oxidative stress
gene expression
copy number
dna methylation