Presence of HPV with overexpression of p16INK4a protein and EBV infection in penile cancer-A series of cases from Brazil Amazon.
Valquíria do Carmo Alves MartinsIsabela Werneck CunhaGiuseppe FigliuoloHeidy Halanna de Melo Farah RondonPaloma Menezes de SouzaFelipe Luz Torres SilvaGuilherme Luz Torres SilvaMichele de Souza BastosDaniel Barros de CastroMonique Freire SantanaRajendranath RamasawmyJosé Eduardo LeviKátia Luz TorresPublished in: PloS one (2020)
p16INK4a positivity presented a high correlation to HPV 16 DNA detection, reinforcing its use as a surrogate marker for HPV-driven cancers. Infection with EBV was quite frequent and its role in epithelial penile oncogenesis needs to be demonstrated.
Keyphrases
- high grade
- epstein barr virus
- diffuse large b cell lymphoma
- cervical cancer screening
- papillary thyroid
- cell proliferation
- prostate cancer
- single molecule
- radical prostatectomy
- circulating tumor
- cell free
- squamous cell
- squamous cell carcinoma
- transcription factor
- small molecule
- young adults
- nucleic acid
- childhood cancer