Modifiable vascular risk factors, white matter disease and cognition in early Parkinson's disease.

Lana M ChahineC Dos SantosM FullardC ScordiaD WeintraubG ErusL RosenthalC DavatzikosC T McMillan

Published in: European journal of neurology (2018)

In early PD, modifiable VRFs are associated with WMH on brain magnetic resonance imaging. Temporal WMH burden predicts decline in verbal memory. WMH may serve as a surrogate marker for the effect of VRFs on cognitive abilities in PD.

Keyphrases

white matter
risk factors
magnetic resonance imaging
working memory
multiple sclerosis
computed tomography
resting state
contrast enhanced
blood brain barrier