Management of Lung Cancer Presenting with Solitary Bone Metastasis.
Colonel Claudiu Eduard NistorAdrian CiucheAnca Pati CucuCornelia NitipirCristina SlavuBogdan SerbanAdrian CursaruBogdan CretuCatalin CirstoiuPublished in: Medicina (Kaunas, Lithuania) (2022)
Lung neoplasm is the main cause of cancer-related mortality, and bone metastasis is among the most common secondary tumors. The vast majority of patients also present with multiple bone metastases, which makes systemic and adjuvant pain therapy preferable to surgery. The optimal approach for a resectable non-small-cell lung tumor that also presents a unique, resectable bone metastasis is not fully established. The number of papers addressing this subject is small, and most are case reports; nevertheless, survival rates seem to increase with radical surgery. The sequencing of local versus systemic treatment should always be discussed within the multidisciplinary team that will choose the best approach for each patient. As targeted systemic therapies become more accessible, radical surgery, together with existing reconstructive methods, will lead to an increase in life expectancy and a better quality of life.
Keyphrases
- minimally invasive
- coronary artery bypass
- bone mineral density
- case report
- end stage renal disease
- single cell
- surgical site infection
- ejection fraction
- soft tissue
- newly diagnosed
- bone loss
- chronic pain
- locally advanced
- early stage
- bone regeneration
- palliative care
- peritoneal dialysis
- type diabetes
- cardiovascular events
- squamous cell carcinoma
- prognostic factors
- spinal cord injury
- spinal cord
- patient reported outcomes
- liver metastases
- coronary artery disease
- drug delivery
- mesenchymal stem cells
- stem cells
- patient reported
- postoperative pain