O1-conotoxin Tx6.7 cloned from the genomic DNA of Conus textile that inhibits calcium currents.

Maojun ZhouManyi YangHuiling WenShun XuCuifang HanYun Wu

Published in: The journal of venomous animals and toxins including tropical diseases (2023)

Our results suggested that direct cloning of conotoxin sequences from the genomic DNA of cone snails would be an alternative approach to obtaining novel conotoxins. Tx6.7 could be used as a probe tool for ion channel research or a therapeutic candidate for novel drug development.

Keyphrases

circulating tumor
cell free
single molecule
copy number
wastewater treatment
nucleic acid
dna methylation
genome wide
genetic diversity