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Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation.

Cunle ZhuShangheng ShiPeng JiangXijian HuangJinxin ZhaoYan JinYuntai ShenXin ZhouHuan LiuJinzhen Cai
Published in: Journal of investigative surgery : the official journal of the Academy of Surgical Research (2023)
Cur combined with DNase-1 was more effective than the two drugs administered alone in alleviating hepatic IRI by inhibiting the generation of NETs. These results also suggested that curcumin combined with DNase-1 was a potential therapeutic strategy to mitigate hepatic IRI.
Keyphrases
  • ischemia reperfusion injury
  • signaling pathway
  • oxidative stress