Prescriber compliance to direct oral anticoagulant labels and impact on outcomes in Thailand.

Phannita WattanaruengchaiSurakit Nathisuwan Wipharak RattanavipanonSuvatna ChulavatnatolJunporn KongwatcharapongPhatcharin MitsuntisukThanaputt ChaiyasothiDuangkamon KritsanapipatArintaya Phrommintikul Nathorn ChaiyakunaprukKhanchit LikittanasombatGregory Y H Lip

Published in: British journal of clinical pharmacology (2020)

Prescribers' compliance to approved indications were high. However, 1/3 of DOAC prescriptions were inconsistent with approved dosing. Dosing deviation was associated with an increase in adverse clinical outcomes.

Keyphrases

drug administration
venous thromboembolism
direct oral anticoagulants
atrial fibrillation
emergency department
type diabetes
skeletal muscle
weight loss
insulin resistance
drug induced