Preoperative stereotactic radiosurgery for patients with 1-4 brain metastases: A single-arm phase 2 trial outcome analysis (NCT03398694).

Namita AgrawalJack M ShiremanKevin ShiueAaron KamerLaKeisha BoydYong ZangNeel MukherjeeJames MillerCharles KulwinAaron Cohen-GadolTroy PaynerChih-Ta LinJesse J SavageBrandon LaneBradley BohnstedtTim LautenschlaegerNaoyuki SaitoMitesh ShahGordon WatsonMahua Dey

Published in: Neuro-oncology practice (2024)

Our data confirms superior local control in patients who received preoperative SRS when compared to historical controls. Further study with a larger randomized cohort of patients is warranted to fully understand the benefits of preoperative SRS.

Keyphrases

brain metastases
patients undergoing
end stage renal disease
small cell lung cancer
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
open label
electronic health record
clinical trial
machine learning
study protocol
data analysis