Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Scott D CollumNing-Yuan ChenAdriana M HernandezAnkit HanmandluHeather SweeneyTinne C J MertensTingting WengFayong LuoJose G MolinaJonathan DaviesIan P HoranNick W MorrellJavier Amione-GuerraOdeaa Al-JabbariKeith YoukerWenchao SunJayakumar RajadasPaul L BollykyBindu H AkkantiSoma JyothulaNeeraj SinhaAshrith GuhaHarry Karmouty-QuintanaPublished in: British journal of pharmacology (2017)
Taken together, our results show evidence of a unique mechanism contributing to PH in the context of lung fibrosis.