The Close Link of Pancreatic Iron With Glucose Metabolism and With Cardiac Complications in Thalassemia Major: A Large, Multicenter Observational Study.
Alessia PepeLaura PistoiaMaria Rita GamberiniLiana CucciaAngelo PelusoGiuseppe MessinaAnna SpasianoMassimo AllòMaria Grazia BisconteMaria Caterina PuttiTommaso CasiniNicola Dello IaconoMauro CelliAngelantonio VitucciPietro GiulianoGiuseppe PeritoreStefania RenneRiccardo RighiVincenzo PositanoVincenzo De SanctisAntonella MeloniPublished in: Diabetes care (2020)
Pancreatic iron is a powerful predictor not only for glucose metabolism but also for cardiac iron and complications, supporting the close link between pancreatic iron and heart disease and the need to intensify iron chelation therapy to prevent both alterations of glucose metabolism and cardiac iron accumulation.