The effects of nitric oxide on coagulation and inflammation in ex-vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass.

Maximilian Valentin MalfertheinerGarrett AshlenMargaret R Passmore Andrew B HaymetWebb I RichardViktor von BahrJonathan E MillarBailey A SchneiderNchafatso G ObonyoBlack DebraBouquet MaheBartnikowski NicoleJacky Y SuenJohn F Fraser

Published in: Artificial organs (2023)

Combined delivery of nitric oxide and heparin did not improve haemocompatibility in either ex vivo model of CPB and ECMO. Anti-inflammatory effects of NO in ECMO systems have to be evaluated further.

Keyphrases

extracorporeal membrane oxygenation
nitric oxide
acute respiratory distress syndrome
anti inflammatory
nitric oxide synthase
respiratory failure
hydrogen peroxide
oxidative stress
venous thromboembolism
mechanical ventilation
growth factor