Smoking-associated DNA methylation markers predict lung cancer incidence.
Yan ZhangMagdeldin ElgizouliBen SchöttkerBernd HolleczekAlexandra NietersHermann BrennerPublished in: Clinical epigenetics (2016)
AHRR, 6p21.33, and F2RL3 methylation in blood DNA are predictive for LC development, which might be useful for identification of risk groups for further specific screening, such as CT examination.
Keyphrases
- dna methylation
- genome wide
- gene expression
- circulating tumor
- computed tomography
- risk factors
- image quality
- cell free
- smoking cessation
- dual energy
- contrast enhanced
- simultaneous determination
- mass spectrometry
- magnetic resonance imaging
- copy number
- positron emission tomography
- liquid chromatography
- magnetic resonance