SARS-CoV-2 spike glycoprotein-reactive T cells can be readily expanded from COVID-19 vaccinated donors.

Pavla TaborskaJan LastovickaDmitry StakheevZuzana Ozaniak StrizovaJirina BartunkovaDaniel Smrz

Published in: Immunity, inflammation and disease (2021)

These findings show for the first time that the combination of the COVID-19 vaccination and ex vivo T cell large-scale expansion of SARS-CoV-2-reactive T cells could be a powerful tool for developing T cell-based adoptive cellular immunotherapy of COVID-19.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
cell therapy
stem cells
mesenchymal stem cells
bone marrow