Stochastic Epigenetic Mutations Are Associated with Risk of Breast Cancer, Lung Cancer, and Mature B-cell Neoplasms.
Amedeo GagliardiPierre-Antoine DuguéTherese H NøstMelissa C SoutheyDaniel D BuchananDaniel F SchmidtEnes MakalicAllison M HodgeDallas R EnglishNicole Wong DooJohn L HopperGianluca SeveriLaura BagliettoAlessio NaccaratiSonia TaralloLuigia PaceVittorio KroghDomenico PalliSalvatore PanicoCarlotta SacerdoteRosario TuminoEiliv LundGraham G GilesBarbara PardiniTorkjel M SandangerJonathan BeesleyPaolo VineisSilvia PolidoroGiovanni FioritoPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
We identified a candidate biomarker for cancer early detection, and we described a carcinogenesis mechanism involving PCR2 complex proteins worthy of further investigations.