Sweetening Inhaled Antibiotic Treatment for Eradication of Chronic Respiratory Biofilm Infection.
Ching-Yee LooWing-Hin LeeGianluca LauretaniSanto ScaliaDavid CipollaDaniela TrainiPaul YoungHui Xin OngPublished in: Pharmaceutical research (2018)
The combination of ciprofloxacin and mannitol may provide an important new strategy to improve antibiotic therapy for the treatment of chronic lung infections. Furthermore, the development of a representative lung model of bacterial biofilm could potentially be used as a platform for future new antimicrobial pre-clinical screening.