Synthesis and in vitro PDT evaluation of new porphyrins containing meso-epoxymethylaryl cationic groups.
Jaqueline CarneiroAlan GonçalvesZehua ZhouKaitlin E GriffinNichole E M KaufmanMaria da Graça Henriques VicentePublished in: Lasers in surgery and medicine (2018)
Our results suggest that cationic methylated porphyrin derivatives are promising PDT photosensitizing agents. The epoxymethyl-containing derivatives showed increased efficacy relative to the neutral analogs, and are good candidates for further investigation. Lasers Surg. Med. 50:566-575, 2018. © 2018 Wiley Periodicals, Inc.