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ACE-27 as a prognostic tool of severe acute toxicities in patients with head and neck cancer treated with chemoradiotherapy: a real-world, prospective, observational study.

Ana Raquel MonteiroAna Rita GarciaTatiana Cunha PereiraFilipa MacedoRita Félix SoaresKayla PereiraTânia SerraLeila KhouriJoão RibeiroMaria Margarida Teixeira
Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)
In patients with head and neck cancer treated with chemoradiotherapy, the presence of moderate to severe comorbidities seems to correlate with higher incidences of severe acute toxicities. ACE-27 may identify patients at higher risk of major toxicities and assist decisions regarding treatment.
Keyphrases
  • rectal cancer
  • locally advanced
  • angiotensin converting enzyme
  • angiotensin ii
  • squamous cell carcinoma
  • high intensity
  • radiation therapy
  • combination therapy