Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability.

Olga EyreRachael A HughesAjay K ThaparEllen LeibenluftArgyris StringarisGeorge Davey SmithEvie StergiakouliStephan CollishawAnita Thapar

Published in: Journal of child psychology and psychiatry, and allied disciplines (2019)

Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group.

Keyphrases

young adults
childhood cancer
early life
depressive symptoms
mental health
attention deficit hyperactivity disorder
sleep quality
autism spectrum disorder
congenital heart disease
working memory
bipolar disorder