Interlaboratory Comparison of Antibody-Free LC-MS/MS Measurements of C-peptide and Insulin.
Annie MoradianElisha GoonatillekeTai-Tu LinMaya Hatten-BeckMichelle EmrickAthena A SchepmoesThomas L FillmoreMichael J MacCossSalvatore SechiKimia SobhaniRandie LittleKuanysh KabytaevJennifer E van EykWei-Jun QianAndrew N HoofnaglePublished in: Clinical chemistry (2024)
Our results suggest that combined LC-MS/MS measurements of C-peptide and insulin are robust and adaptable and that standardization with a reference measurement procedure could allow accurate and precise measurements across sites, which could be important to diabetes research and help patient care in the future.