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AKR1B10 accelerates glycolysis through binding HK2 to promote the malignant progression of oral squamous cell carcinoma.
Ye Cai
Huiling Li
Diya Xie
Yanan Zhu
Published in:
Discover oncology (2024)
To sum up, AKR1B10 could bind to HK2 to accelerate glycolysis, thereby facilitating the proliferation, migration, invasion and EMT of OSCC cells.
Keyphrases
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induced apoptosis
signaling pathway
cell cycle arrest
high glucose
epithelial mesenchymal transition
cell migration
cell death
oxidative stress
dna binding
pi k akt