Comparative analysis of two arecoline-induced oral submucous fibrosis models.

Shijie TangLanxin JiangYing ZhouTong ZhouYang PengShuting ZhouYuan YueXiaoqiang XiaJing LiQianming ChenYuchen Jiang Xiaodong Feng

Published in: Oral diseases (2023)

Both the water drinking and injection mouse models effectively induced OSF, but the water-drinking model better mirrored the observed pathogenesis in patients with OSF. These models provide valuable tools for investigating the mechanisms underlying OSF.

Keyphrases

high glucose
diabetic rats
mouse model
drug induced
oxidative stress
alcohol consumption