Effects of Cudrania tricuspidata and Sargassum fusiforme extracts on hair growth in C57BL/6 mice.
Priyanka RajanPremkumar NatrajNak Hyoung KimJae-Hoon KimHyuk Joon ChoiChang Hoon HanPublished in: Laboratory animal research (2023)
Our results suggest that C. tricuspidata and/or S. fusiforme extracts show potential hair growth efficacy by upregulating anagen factor genes, including β-catenin, Pdgf, Vegf, and Wnts, and downregulating catagen-telogen factor genes, including Osm, in C57BL/6 mice. The findings suggest that C. tricuspidata and/or S. fusiforme extracts are potential drug candidates to treat alopecia.
Keyphrases
- high fat diet induced
- genome wide
- bioinformatics analysis
- cell proliferation
- genome wide identification
- human health
- epithelial mesenchymal transition
- endothelial cells
- vascular endothelial growth factor
- type diabetes
- gene expression
- metabolic syndrome
- genome wide analysis
- insulin resistance
- wild type
- risk assessment
- skeletal muscle
- transcription factor
- adverse drug
- electronic health record