Telomere length and signal joint T-cell receptor rearrangement excision circles as biomarkers for chronological age estimation.
Mostafa Ali ElmadawyOmnia A AbdullahWalaa Bayoumie El GazzarEnas Sebaey AhmadSeham Gouda AmeenAfaf AbdelkaderPublished in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2021)
The TRF length was shortened with increased age (r = -0.722, p < 0.001). The sjTRECs were also decreased with increased age (r = -0.831, p < 0.001). Stronger coefficient and lower standard error of the estimate was obtained when multiple regression analysis for age prediction based on the values of both methods was applied (r = -0.876, p < 0.001).