Measuring hydroxyurea adherence by pharmacy and laboratory data compared with video observation in children with sickle cell disease.
Susan E CrearyDeena ChisolmJoseph StanekKathleen NevilleUttam GargJane Silva HankinsSarah H O'BrienPublished in: Pediatric blood & cancer (2020)
Commonly used tools to measure hydroxyurea adherence may not correlate with or be valid compared with video adherence. Future studies to refine these measures are needed to effectively target adherence interventions to children with SCD who have the potential to benefit. (ClinicalTrials.gov NCT02578017).