Impact of pneumococcal vaccine response on asthma exacerbation frequency in young children.

Claudia P EisenlohrEsther M ChartrandMarta R BarzagaMiguel J Lanz

Published in: Immunity, inflammation and disease (2020)

This subset of children with exacerbation-prone asthma had poor antibody titer response to Streptococcus pneumoniae, even with prior complete PCV-13 immunization. Identification of low antibody responses to PV serotypes may provide a targeted therapeutic approach to reduce wheezing exacerbations in a precise asthma phenotype in children.

Keyphrases

chronic obstructive pulmonary disease
lung function
young adults
allergic rhinitis
cystic fibrosis
acute respiratory distress syndrome
bioinformatics analysis