Tandem repeat variation near the HIC1 (hypermethylated in cancer 1) promoter predicts outcome of oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.

Satoshi OkazakiMarta SchirripaFotios LoupakisShu CaoWu ZhangDongyun YangYan NingMartin D BergerYuji MiyamotoMitsukuni SuenagaSyma IqubalAfsaneh BarziChiara CremoliniAlfredo FalconeFrancesca BattaglinLisa SalvatoreBeatrice BorelliTimothy G HelentjarisHeinz-Josef Lenz

Published in: Cancer (2017)

The current findings suggest that the VNTR sequence near HIC1 could be a predictive marker for oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Cancer 2017;123:4506-14. © 2017 American Cancer Society.

Keyphrases

metastatic colorectal cancer
papillary thyroid
squamous cell
dna methylation
gene expression
locally advanced
young adults
childhood cancer
rectal cancer
amino acid