In vivo evaluation of β-CS/n-HA with different physical properties as a new bone graft material.

The composite β-CS/HPa (30/70) as biodegradable bone substitute that not only enhance bone generation but also accelerate the formation of Haversian system. We used the composite in a powder form and examined its suitability as artificial bone graft; yet the mechanical properties have shown that 30/70 ratio of β-CS/HPa offer suitable mechanical strength to be employed as a solid-shaped implants.