Thyrotrophin receptor antibody concentration and activity, several years after treatment for Graves' disease.

Preethi NallaStuart YoungJane SandersJoanne CarterMohamed A AdlanKatarzyna KabelisShu ChenJadwiga FurmaniakBernard Rees SmithLakdasa D K E Premawardhana

Published in: Clinical endocrinology (2018)

TRAb levels generally decreased after treatment but persisted for over 5 years in some patients. TRAb activity was predominantly stimulatory, with only one patient demonstrating TSBAb. A large proportion of patients were TgAb/TPOAb-positive at follow-up. All treatment modalities reduced TRAb concentrations; however, surgery was most effective.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
minimally invasive
coronary artery disease
case report
binding protein