tsRNA-15797-modified BMSC-derived exosomes mediate LFNG to induce angiogenesis in osteonecrosis of the femoral head.

Shanhong FangMengqiang YouJie WeiPeng Chen

Published in: Turkish journal of biology = Turk biyoloji dergisi (2023)

We successfully constructed tsRNA-15797-modified BMSC-derived exosomes and demonstrated that it induced the angiogenesis of HUVECs by targeting the down-regulation of LFNG. Thus, tsRNA-15797-loaded BMSCs-derived exosomes may be a potential target therapy drug for ONFH.

Keyphrases

mesenchymal stem cells
stem cells
endothelial cells
vascular endothelial growth factor
high glucose
wound healing
drug delivery
emergency department
wastewater treatment
cancer therapy
bone marrow
climate change