The impact of obesity and endocrine therapy on the prognosis of premenopausal women with hormone receptor-positive breast cancer: A single-institute retrospective study.
Yukinori OzakiJun MasudaAkemi KataokaTakahiro KogawaTomomi AbeHidetomo MorizonoLina InagakiFumikata HaraToshimi TakanoTakayuki UenoShinji OhnoPublished in: Cancer reports (Hoboken, N.J.) (2022)
High BMI was associated with worse prognosis in premenopausal patients with HR-positive BC who received adjuvant TAM. The role of OFS as adjuvant endocrine therapy remains unclear, and further studies are required to explore the adequate management of obese premenopausal patients.
Keyphrases
- positive breast cancer
- postmenopausal women
- metabolic syndrome
- weight loss
- early stage
- type diabetes
- ejection fraction
- newly diagnosed
- weight gain
- insulin resistance
- early breast cancer
- breast cancer risk
- patient reported outcomes
- mesenchymal stem cells
- skeletal muscle
- high fat diet induced
- cell therapy
- smoking cessation