Coexistent HCN4 and GATA5 Rare Variants and Atrial Fibrillation in a Large Spanish Family.

Alfonso FraileJorge CebriánIsrael Thuissard-VasalloSara Pérez-MartínRaquel CasadoBelén Gil-FournierJoaquín Alonso-MartínJuan TamargoRicardo CaballeroEva DelpónFrancisco G Cosío

Published in: The Canadian journal of cardiology (2024)

The coincidence of 2 rare gene variants was independently associated with AF, but functional studies do not allow the postulation of the arrhythmogenic mechanisms involved.

Keyphrases

copy number
atrial fibrillation
genome wide
oral anticoagulants
catheter ablation
heart failure
left atrial
left atrial appendage
transcription factor
direct oral anticoagulants
dna methylation
percutaneous coronary intervention
case control
mitral valve