The Salivary Microbiome and Predicted Metabolite Production Are Associated with Barrett's Esophagus and High-Grade Dysplasia or Adenocarcinoma.

Quinn S Solfisburg Federico Baldini Brittany Baldwin-Hunter George I Austin Harry H Lee Heekuk Park Daniel E Freedberg Charles J Lightdale Tal Korem Julian A Abrams

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)

There is an association between oral dysbiosis and HGD/EAC. Further work is needed to establish the diagnostic, predictive, and causal potential of this relationship.

Keyphrases

high grade
low grade
squamous cell carcinoma
locally advanced
human health
risk assessment
rectal cancer
endoscopic submucosal dissection