Transcriptomic analysis of hidradenitis suppurativa skin suggests roles for multiple inflammatory pathways in disease pathogenesis.

Beth E RumbergerErika L BoarderSherry L OwensMichael D Howell

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)

These data illustrate the diverse immune activation in lesional HS skin and suggest that deeper interrogation of the disease heterogeneity may reveal unique opportunities for targeted therapies in designated subpopulations.

Keyphrases

hidradenitis suppurativa
soft tissue
single cell
wound healing
oxidative stress
genome wide
electronic health record
dna methylation