Long-term lithium therapy and risk of chronic kidney disease in bipolar disorder: A historical cohort study.
Mehak PahwaBoney JosephNicolas A NunezGregory D JenkinsColin L ColbyKianoush B Kashaninull Marin VeldicKatherine M MooreHannah K BetcherAysegul OzerdemAlfredo B Cuellar BarbozaSusan L McElroyJoanna M BiernackaMark A FryeBalwinder SinghPublished in: Bipolar disorders (2021)
CKD was observed in one fourth of patients with BD receiving LTLT. There was no significant difference in the progression of CKD among Li continuers versus discontinuers, at the mean follow-up duration of 4.2 years, after the CKD diagnosis. Progression of CKD could be influenced by existing comorbidities and may not necessarily be due to lithium alone.