Differences in inherited risk among relatives of hereditary prostate cancer patients using genetic risk score.

Brian T HelfandHaitao ChenRichard J FantusCarly A ConranCharles B BrendlerSiquan Lilly ZhengPatrick C WalshWilliam B Isaacs Jianfeng Xu

Published in: The Prostate (2018)

GRS is an easy-to-interpret, objective measure that can be used to assess differences in PCa risk among family members of affected men. GRS allows for further differentiation among family members, providing better risk assessment. While prospective validation studies are required, this information can help guide relatives in regards to the time of initiation and frequency of PCa screening.

Keyphrases

prostate cancer
risk assessment
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
radical prostatectomy
peritoneal dialysis
healthcare
gene expression
heavy metals
copy number