Genistein reverses the effect of 17β-estradiol on exacerbating experimental occlusal interference-induced chronic masseter hyperalgesia in ovariectomised rats.
Yun LiuXiao-Yu ZhangYing-Ying FanXiao-Xiang XuQiu-Fei XiePublished in: Journal of oral rehabilitation (2021)
Female rats showed greater masseter hyperalgesia than males under EOI. Genistein antagonised the facilitation of EOI-induced chronic masseter hyperalgesia by E2 probably through inhibiting TRPV1 in the TG.